a public good project by the
Synthesis
Company
of California

© 2026

Wolfgang Froestl | doi.page

0 works0 citations0 h-index

Wolfgang Froestl

AC Immune (Switzerland)(CH)École Polytechnique Fédérale de Lausanne(CH)

Publications by Year

Research Areas

Neuroscience and Neuropharmacology Research, Neurotransmitter Receptor Influence on Behavior, Nicotinic Acetylcholine Receptors Study, Receptor Mechanisms and Signaling, Biochemical Analysis and Sensing Techniques

Most-Cited Works

→ GABAB-receptor subtypes assemble into functional heteromeric complexes(1998)1,174 cited
→ Expression cloning of GABAB receptors uncovers similarity to metabotropic glutamate receptors(1997)1,024 cited
→ Epilepsy, Hyperalgesia, Impaired Memory, and Loss of Pre- and Postsynaptic GABAB Responses in Mice Lacking GABAB(1)(2001)538 cited
→ Genetic and Pharmacological Evidence of a Role for GABAB Receptors in the Modulation of Anxiety- and Antidepressant-Like Behavior(2004)353 cited
→ CGP 35348: a centrally active blocker of GABAB receptors(1990)309 cited
→ C-Terminal Interaction Is Essential for Surface Trafficking But Not for Heteromeric Assembly of GABA_BReceptors(2001)306 cited

Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501.

(2001)

→ Redistribution of GABA_B(1)Protein and Atypical GABA_BResponses in GABA_B(2)-Deficient Mice(2004)226 cited

→ Positive Allosteric Modulation of Native and Recombinant γ-Aminobutyric Acid_BReceptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its Aldehyde Analog CGP13501(2001)218 cited

→ Mutagenesis and Modeling of the GABAB Receptor Extracellular Domain Support a Venus Flytrap Mechanism for Ligand Binding(1999)217 cited