Rinpei Niwa
Kyowa Kirin (Japan)(JP)Kyowa Kirin (France)(FR)
Publications by Year
Research Areas
Monoclonal and Polyclonal Antibodies Research, Glycosylation and Glycoproteins Research, Viral Infectious Diseases and Gene Expression in Insects, Galectins and Cancer Biology, Chronic Lymphocytic Leukemia Research
Most-Cited Works
- → Establishment of FUT8 knockout Chinese hamster ovary cells: An ideal host cell line for producing completely defucosylated antibodies with enhanced antibody‐dependent cellular cytotoxicity(2004)568 cited
- → Defucosylated Chimeric Anti-CC Chemokine Receptor 4 IgG1 with Enhanced Antibody-Dependent Cellular Cytotoxicity Shows Potent Therapeutic Activity to T-Cell Leukemia and Lymphoma(2004)324 cited
- → IgG subclass-independent improvement of antibody-dependent cellular cytotoxicity by fucose removal from Asn297-linked oligosaccharides(2005)239 cited
- → Enhancement of the Antibody-Dependent Cellular Cytotoxicity of Low-Fucose IgG1 Is Independent of FcγRIIIa Functional Polymorphism(2004)228 cited
- → Enhanced Natural Killer Cell Binding and Activation by Low-Fucose IgG1 Antibody Results in Potent Antibody-Dependent Cellular Cytotoxicity Induction at Lower Antigen Density(2005)188 cited
- → Engineered Antibodies of IgG1/IgG3 Mixed Isotype with Enhanced Cytotoxic Activities(2008)186 cited
- → Engineering Chinese hamster ovary cells to maximize effector function of produced antibodies using FUT8 siRNA(2004)174 cited
- → Engineered therapeutic antibodies with improved effector functions(2009)152 cited
- Improving effector functions of antibodies for cancer treatment: Enhancing ADCC and CDC.(2009)
- → A Nonfucosylated Anti-HER2 Antibody Augments Antibody-Dependent Cellular Cytotoxicity in Breast Cancer Patients(2007)107 cited