Carla A. Donatelli

Publications by Year

Research Areas

Microtubule and mitosis dynamics, Ubiquitin and proteasome pathways, PI3K/AKT/mTOR signaling in cancer, Phytochemicals and Antioxidant Activities, Protein Kinase Regulation and GTPase Signaling

Most-Cited Works

• → Discovery of GSK2126458, a Highly Potent Inhibitor of PI3K and the Mammalian Target of Rapamycin(2010)368 cited
• → Discovery of GSK1070916, a Potent and Selective Inhibitor of Aurora B/C Kinase(2010)109 cited
• → Novel ATP-Competitive Kinesin Spindle Protein Inhibitors(2007)74 cited
• → Discovery of the First Potent and Selective Inhibitor of Centromere-Associated Protein E: GSK923295(2010)64 cited
• → Design and Optimization of Sulfone Pyrrolidine Sulfonamide Antagonists of Transient Receptor Potential Vanilloid-4 with in Vivo Activity in a Pulmonary Edema Model(2018)34 cited
• → Discovery of Pyrrolidine Sulfonamides as Selective and Orally Bioavailable Antagonists of Transient Receptor Potential Vanilloid-4 (TRPV4)(2018)27 cited
• → Discovery of a new series of Aurora inhibitors through truncation of GSK1070916(2010)19 cited
• → Design and Optimization of an Acyclic Amine Series of TRPV4 Antagonists by Electronic Modulation of Hydrogen Bond Interactions(2020)12 cited
• → Abstract C62: Identification of GSK2126458, a highly potent inhibitor of phosphoinositide 3-kinase (PI3K) and the mammalian target of rapamycin (mTOR)(2009)4 cited
• → CCDC 1989126: Experimental Crystal Structure Determination(2020)