Ellen M. van der Aar
Galapagos (Belgium)(BE)
Publications by Year
Research Areas
Glutathione Transferases and Polymorphisms, Genomics, phytochemicals, and oxidative stress, Osteoarthritis Treatment and Mechanisms, Rheumatoid Arthritis Research and Therapies, Reproductive Health and Contraception
Most-Cited Works
- → Safety, tolerability, pharmacokinetics, and pharmacodynamics of GLPG1690, a novel autotaxin inhibitor, to treat idiopathic pulmonary fibrosis (FLORA): a phase 2a randomised placebo-controlled trial(2018)232 cited
- → Preclinical Characterization of GLPG0634, a Selective Inhibitor of JAK1, for the Treatment of Inflammatory Diseases(2013)229 cited
- → Triazolopyridines as Selective JAK1 Inhibitors: From Hit Identification to GLPG0634(2014)118 cited
- → Discovery and Optimization of an Azetidine Chemical Series As a Free Fatty Acid Receptor 2 (FFA2) Antagonist: From Hit to Clinic(2014)109 cited
- → Structure-activity relationships for chemical and glutathione S-transferase-catalysed glutathione conjugation reactions of a series of 2-substituted 1-chloro-4-nitrobenzenes(1996)20 cited
- → Enzyme kinetics and substrate selectivities of rat glutathione S-transferase isoenzymes towards a series of new 2-substituted 1-chloro-4-nitrobenzenes(1996)19 cited
- → Strategies to Characterize the Mechanisms of Action and the Active Sites of GlutathioneS-Transferases: A Review(1998)18 cited
- → The lipid peroxidation product 4-hydroxy-2,3-trans-1 nonenal decreases rat intestinal smooth muscle function in-vitro by alkylation of sulphydryl groups(1991)11 cited
- → ADAMTS-5 inhibitor GLPG1972, a potential new treatment in osteoarthritis, shows favorable safety, pharmacokinetics and pharmacodynamics in healthy subjects(2018)11 cited
- → 4- or 5-(ω-Aminoalkyl)Thiazoles and Derivatives; New Selective H2-Receptor Agonists(1991)10 cited