Masanori Okaniwa
Publications by Year
Research Areas
Melanoma and MAPK Pathways, Synthesis and biological activity, Cytokine Signaling Pathways and Interactions, interferon and immune responses, Cancer Mechanisms and Therapy
Most-Cited Works
- → Overcoming mTOR resistance mutations with a new-generation mTOR inhibitor(2016)473 cited
- → STING agonist delivery by tumour-penetrating PEG-lipid nanodiscs primes robust anticancer immunity(2022)299 cited
- → Aneuploidy generates proteotoxic stress and DNA damage concurrently with p53-mediated post-mitotic apoptosis in SAC-impaired cells(2015)198 cited
- → A Kinase Inhibitor Targeted to mTORC1 Drives Regression in Glioblastoma(2017)177 cited
- → Antitumor Activity of the Selective Pan-RAF Inhibitor TAK-632 in BRAF Inhibitor-Resistant Melanoma(2013)123 cited
- → Discovery of a Selective Kinase Inhibitor (TAK-632) Targeting Pan-RAF Inhibition: Design, Synthesis, and Biological Evaluation of C-7-Substituted 1,3-Benzothiazole Derivatives(2013)112 cited
- → Design and Synthesis of Novel DFG-Out RAF/Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Inhibitors. 1. Exploration of [5,6]-Fused Bicyclic Scaffolds(2012)77 cited
- → TAK-676: A Novel Stimulator of Interferon Genes (STING) Agonist Promoting Durable IFN-dependent Antitumor Immunity in Preclinical Studies(2022)51 cited
- → Diastereoselective allylation and alkylation of optically active imines with metallic samarium and a catalytic amount of iodine(1999)43 cited
- → Design and synthesis of selective CDK8/19 dual inhibitors: Discovery of 4,5-dihydrothieno[3′,4′:3,4]benzo[1,2-d]isothiazole derivatives(2017)37 cited