Sriram Tyagarajan
Merck & Co., Inc., Rahway, NJ, USA (United States)(US)
Publications by Year
Research Areas
Pain Mechanisms and Treatments, Computational Drug Discovery Methods, Catalytic C–H Functionalization Methods, Ion channel regulation and function, Chemical Synthesis and Analysis
Most-Cited Works
- → The medicinal chemist's toolbox for late stage functionalization of drug-like molecules(2015)1,686 cited
- → An orally available non-nucleotide STING agonist with antitumor activity(2020)621 cited
- → Exploration of the internal cavity of histone deacetylase (HDAC) with selective HDAC1/HDAC2 inhibitors (SHI-1:2)(2007)187 cited
- → Design, Synthesis and Evaluation of Substituted Triarylnipecotic Acid Derivatives as GABA Uptake Inhibitors: Identification of a Ligand with Moderate Affinity and Selectivity for the Cloned Human GABA Transporter GAT-3(1994)124 cited
- → Design and Synthesis of Novel α1a Adrenoceptor-Selective Antagonists. 1. Structure−Activity Relationship in Dihydropyrimidinones(1999)112 cited
- → Bismuth Acetate as a Catalyst for the Sequential Protodeboronation of Di- and Triborylated Indoles(2016)42 cited
- → Design and Synthesis of Novel α1a Adrenoceptor-Selective Antagonists. 2. Approaches To Eliminate Opioid Agonist Metabolites via Modification of Linker and 4-Methoxycarbonyl-4-phenylpiperidine Moiety(1999)41 cited
- → Synthesis of pyrimidines from ketones using microwave irradiation(2005)35 cited
- → In vitro studies on L-771,688 (SNAP 6383), a new potent and selective α1A-adrenoceptor antagonist(2000)33 cited
- → Electrochemical bromination of late stage intermediates and drug molecules(2017)31 cited