Kajsa P. Kanebratt

Publications by Year

Research Areas

Pharmacogenetics and Drug Metabolism, Drug Transport and Resistance Mechanisms, Pancreatic function and diabetes, 3D Printing in Biomedical Research, Drug-Induced Hepatotoxicity and Protection

Most-Cited Works

• → Evaluation of HepaRG Cells as an in Vitro Model for Human Drug Metabolism Studies(2008)343 cited
• → Functional coupling of human pancreatic islets and liver spheroids on-a-chip: Towards a novel human ex vivo type 2 diabetes model(2017)264 cited
• → The HepaRG cell line: a uniquein vitrotool for understanding drug metabolism and toxicology in human(2012)238 cited
• → HepaRG Cells as an in Vitro Model for Evaluation of Cytochrome P450 Induction in Humans(2007)206 cited
• → Cytochrome P450 Induction by Rifampicin in Healthy Subjects: Determination Using the Karolinska Cocktail and the Endogenous CYP3A4 Marker 4β-Hydroxycholesterol(2008)132 cited
• → 4β‐Hydroxycholesterol as an endogenous marker for CYP3A4/5 activity. Stability and half‐life of elimination after induction with rifampicin(2008)122 cited
• → The TM6SF2 E167K genetic variant induces lipid biosynthesis and reduces apolipoprotein B secretion in human hepatic 3D spheroids(2019)120 cited
• → Primary Human Hepatocyte Spheroid Model as a 3D In Vitro Platform for Metabolism Studies(2020)62 cited
• → Critical differences in drug metabolic properties of human hepatic cellular models, including primary human hepatocytes, stem cell derived hepatocytes, and hepatoma cell lines(2018)55 cited
• → Managing the Risk of CYP3A Induction in Drug Development: A Strategic Approach(2016)51 cited