Edwin J. Iwanowicz
Madera BioSciences (United States)(US)
Publications by Year
Research Areas
Cancer, Hypoxia, and Metabolism, Mitochondrial Function and Pathology, Peptidase Inhibition and Analysis, RNA modifications and cancer, Biochemical and Molecular Research
Most-Cited Works
- → Mitochondrial Protease ClpP is a Target for the Anticancer Compounds ONC201 and Related Analogues(2019)197 cited
- → A mild and efficient method for the preparation of guanidines(1992)132 cited
- → Preparation ofN,N'-bis-tert-Butoxycarbonylthiourea(1993)82 cited
- → The synthesis of either (+) or (−) trans-2,5-dimethylpyrrolidine(1987)57 cited
- → Imidazoquinoxaline Src-Family Kinase p56Lck Inhibitors: SAR, QSAR, and the Discovery of (S)-N-(2-Chloro-6-methylphenyl)-2-(3-methyl-1-piperazinyl)imidazo- [1,5-a]pyrido[3,2-e]pyrazin-6-amine (BMS-279700) as a Potent and Orally Active Inhibitor with Excellent in Vivo Antiinflammatory Activity(2004)55 cited
- → Discovery and Development of 5-[(5S,9R)-9- (4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1- methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]non- 7-yl-methyl]-3-thiophenecarboxylic Acid (BMS-587101)A Small Molecule Antagonist of Leukocyte Function Associated Antigen-1(2006)51 cited
- → Acridone-Based Inhibitors of Inosine 5‘-Monophosphate Dehydrogenase: Discovery and SAR Leading to the Identification of N-(2-(6-(4-Ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2- fluoro-9-oxo-9,10-dihydroacridine-3-carboxamide (BMS-566419)(2007)49 cited
- → An enantio- and erythro-selective lithium enolate derived from a vinylogous urethane: its application as a C4 synthon to the virginiamycin M2 problem(1986)47 cited
- → Highly diastereoselective alkylation reactions of vinylogous urethanes derived from simple tetronic acids(1988)43 cited
- → Potent ClpP agonists with anticancer properties bind with improved structural complementarity and alter the mitochondrial N-terminome(2022)43 cited