Francis Bourbonais
Pfizer (United States)(US)BioWorks (United States)(US)
Publications by Year
Research Areas
Pancreatic function and diabetes, Metabolism, Diabetes, and Cancer, Diabetes Treatment and Management, Protein Kinase Regulation and GTPase Signaling, Stress Responses and Cortisol
Most-Cited Works
- → Crystallographic structure of a small molecule SIRT1 activator-enzyme complex(2015)198 cited
- → The Activation of Glycogen Synthase by Insulin Switches from Kinase Inhibition to Phosphatase Activation during Adipogenesis in 3T3-L1 Cells(1998)121 cited
- → Discovery of (S)-6-(3-Cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic Acid as a Hepatoselective Glucokinase Activator Clinical Candidate for Treating Type 2 Diabetes Mellitus(2011)115 cited
- → Pyridones as glucokinase activators: Identification of a unique metabolic liability of the 4-sulfonyl-2-pyridone heterocycle(2009)80 cited
- → Nucleotide sequence and expression of the mouse corticotropin-releasing hormone gene(1991)52 cited
- → Novel and selective spiroindoline-based inhibitors of sky kinase(2011)48 cited
- → Comparison of Proteomic Quantification Approaches for Hepatic Drug Transporters: Multiplexed Global Quantitation Correlates with Targeted Proteomic Quantitation(2018)28 cited
- → Pyrimidone-based series of glucokinase activators with alternative donor–acceptor motif(2013)22 cited
- → Expression of Corticotropin-Releasing Hormone Transgenes in Neurons of Adult and Developing Mice(1994)19 cited
- → Modulation of glucokinase by glucose, small-molecule activator and glucokinase regulatory protein: steady-state kinetic and cell-based analysis(2011)12 cited