Katherine S. Fenner

Publications by Year

Research Areas

Drug Transport and Resistance Mechanisms, Pharmacogenetics and Drug Metabolism, Pharmacological Effects and Toxicity Studies, HIV/AIDS drug development and treatment, Computational Drug Discovery Methods

Most-Cited Works

• → Development of a new permeability assay using low‐efflux MDCKII cells(2011)314 cited
• → Mechanistic Pharmacokinetic Modeling for the Prediction of Transporter-Mediated Disposition in Humans from Sandwich Culture Human Hepatocyte Data(2012)241 cited
• → Intracellular Drug Concentrations and Transporters: Measurement, Modeling, and Implications for the Liver(2013)230 cited
• → Understanding the Critical Disposition Pathways of Statins to Assess Drug–Drug Interaction Risk During Drug Development: It's Not Just About OATP1B1(2012)194 cited
• → A comprehensive non‐clinical evaluation of the CNS penetration potential of antimuscarinic agents for the treatment of overactive bladder(2011)178 cited
• → pH-Dependent Solubility and Permeability Criteria for Provisional Biopharmaceutics Classification (BCS and BDDCS) in Early Drug Discovery(2012)163 cited
• → Mechanistic insights from comparing intrinsic clearance values between human liver microsomes and hepatocytes to guide drug design(2012)152 cited
• → Targeting Intestinal Transporters for Optimizing Oral Drug Absorption(2010)128 cited
• → Solitary Inhibition of the Breast Cancer Resistance Protein Efflux Transporter Results in a Clinically Significant Drug-Drug Interaction with Rosuvastatin by Causing up to a 2-Fold Increase in Statin Exposure(2015)97 cited
• → Absolute immunoquantification of the expression of ABC transporters P-glycoprotein, breast cancer resistance protein and multidrug resistance-associated protein 2 in human liver and duodenum(2011)81 cited