Ole Henrik Brekke
Br. Birkeland (Norway)(NO)
Publications by Year
Research Areas
Monoclonal and Polyclonal Antibodies Research, Glycosylation and Glycoproteins Research, Complement system in diseases, Blood groups and transfusion, Protein purification and stability
Most-Cited Works
- → Therapeutic antibodies for human diseases at the dawn of the twenty-first century(2002)550 cited
- → The structural requirements for complement activation by IgG: does it hinge on the hinge?(1995)137 cited
- → Comparisons of the Ability of Human IgG3 Hinge Mutants, IgM, IgE, and IgA2, to Form Small Immune Complexes: A Role for Flexibility and Geometry(1998)102 cited
- → Identification of scFv antibody fragments that specifically recognise the heroin metabolite 6-monoacetylmorphine but not morphine(2003)79 cited
- → Lysine 322 in the human IgG3 CH2 domain is crucial for antibody dependent complement activation(2000)71 cited
- → Construction, evaluation and refinement of a large human antibody phage library based on the IgD and IgM variable gene repertoire(2005)57 cited
- → Activation of complement by an IgG molecule without a genetic hinge(1993)44 cited
- → One disulfide bond in front of the second heavy chain constant region is necessary and sufficient for effector functions of human IgG3 without a genetic hinge.(1994)35 cited
- → Chimeric mouse human IgG3 antibodies with an IgG4‐like hinge region induce complement‐mediated lysis more efficiently than IgG3 with normal hing(1991)33 cited
- → Human IgG isotype‐specific amino acid residues affecting complement‐mediated cell lysis and phagocytosis(1994)32 cited