Sindhu Carmen Sivakumaren
Harvard University(US)Dana-Farber Cancer Institute(US)
Publications by Year
Research Areas
PI3K/AKT/mTOR signaling in cancer, Cancer-related Molecular Pathways, Biochemical and Molecular Research, Microtubule and mitosis dynamics, Protein Degradation and Inhibitors
Most-Cited Works
- → Phosphorylation-mediated PTEN conformational closure and deactivation revealed with protein semisynthesis(2013)97 cited
- → A Chemoproteomic Strategy for Direct and Proteome-Wide Covalent Inhibitor Target-Site Identification(2018)90 cited
- → Gene expression in human oral squamous cell carcinoma is influenced by risk factor exposure(2009)66 cited
- → Targeting the PI5P4K Lipid Kinase Family in Cancer Using Covalent Inhibitors(2020)55 cited
- → Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells(2019)36 cited
- → Discovery and Structure–Activity Relationship Study of ( Z )-5-Methylenethiazolidin-4-one Derivatives as Potent and Selective Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors(2020)28 cited
- → Structure–Activity Relationship Study of Covalent Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors(2019)17 cited
- → Targeting the PI5P4K lipid kinase family in cancer using novel covalent inhibitors(2019)1 cited
- → Combined inhibition of mTOR and PIKKs exploits replicative and checkpoint vulnerabilities to induce death of PI3K-activated triple-negative breast cancer cells(2019)1 cited
- → Abstract B103: Torin2 and related analogs exploit replicative and checkpoint vulnerabilities to induce death of triple-negative breast cancer cells(2019)