Jacob T. Bush
Age UK(GB)
Publications by Year
Research Areas
Click Chemistry and Applications, Protein Degradation and Inhibitors, Ubiquitin and proteasome pathways, Chemical Synthesis and Analysis, Peptidase Inhibition and Analysis
Most-Cited Works
- → 5-Carboxy-8-hydroxyquinoline is a broad spectrum 2-oxoglutarate oxygenase inhibitor which causes iron translocation(2013)163 cited
- → Selectively Targeting the Kinome-Conserved Lysine of PI3Kδ as a General Approach to Covalent Kinase Inhibition(2017)112 cited
- → Profiling Sulfur(VI) Fluorides as Reactive Functionalities for Chemical Biology Tools and Expansion of the Ligandable Proteome(2023)83 cited
- → A Cell‐Permeable Ester Derivative of the JmjC Histone Demethylase Inhibitor IOX1(2014)76 cited
- → A direct-to-biology high-throughput chemistry approach to reactive fragment screening(2021)69 cited
- → A Photoaffinity‐Based Fragment‐Screening Platform for Efficient Identification of Protein Ligands(2020)57 cited
- → Studies on Deacetoxycephalosporin C Synthase Support a Consensus Mechanism for 2-Oxoglutarate Dependent Oxygenases(2014)53 cited
- → Novel WRN Helicase Inhibitors Selectively Target Microsatellite-Unstable Cancer Cells(2024)45 cited
- → Efficient Ligand Discovery Using Sulfur(VI) Fluoride Reactive Fragments(2023)41 cited
- → The Ugi four-component reaction enables expedient synthesis and comparison of photoaffinity probes(2013)40 cited