James Chapman
Newcastle Hospitals - Campus for Ageing and Vitality(GB)Newcastle University(GB)
Publications by Year
Research Areas
Telomeres, Telomerase, and Senescence, Neutrophil, Myeloperoxidase and Oxidative Mechanisms, Cancer therapeutics and mechanisms, Mitochondrial Function and Pathology, Genetics, Aging, and Longevity in Model Organisms
Most-Cited Works
- → Apoptotic stress causes mtDNA release during senescence and drives the SASP(2023)530 cited
- → Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence(2019)496 cited
- → Mitochondrial dysfunction and cell senescence: deciphering a complex relationship(2019)314 cited
- → Neutrophils induce paracrine telomere dysfunction and senescence in ROS‐dependent manner(2021)201 cited
- → Clearance of senescent cells during cardiac ischemia–reperfusion injury improves recovery(2020)163 cited
- → The Maintenance of Mitochondrial DNA Integrity and Dynamics by Mitochondrial Membranes(2020)96 cited
- → Rapamycin improves healthspan but not inflammaging in nfκb1−/− mice