Frank Breitenbuecher
Publications by Year
Research Areas
Chronic Myeloid Leukemia Treatments, Acute Myeloid Leukemia Research, Lung Cancer Treatments and Mutations, Gastrointestinal Tumor Research and Treatment, Colorectal Cancer Treatments and Studies
Most-Cited Works
- → Clinical resistance to the kinase inhibitor PKC412 in acute myeloid leukemia by mutation of Asn-676 in the FLT3 tyrosine kinase domain(2005)267 cited
- → Insertion of FLT3 internal tandem duplication in the tyrosine kinase domain-1 is associated with resistance to chemotherapy and inferior outcome(2009)265 cited
- → Inactivation of Capicua drives cancer metastasis(2016)166 cited
- → Identification of a novel type of ITD mutations located in nonjuxtamembrane domains of the FLT3 tyrosine kinase receptor(2008)141 cited
- → Efficacy and safety of imatinib in adult patients with c-kit–positive acute myeloid leukemia(2004)135 cited
- → Stabilization of Physical RAF/14-3-3 Interaction by Cotylenin A as Treatment Strategy for RAS Mutant Cancers(2013)126 cited
- → A novel molecular mechanism of primary resistance to FLT3-kinase inhibitors in AML(2009)122 cited
- → Targeting MCL-1 sensitizes FLT3-ITD-positive leukemias to cytotoxic therapies(2012)85 cited
- → DOG1 Regulates Growth and IGFBP5 in Gastrointestinal Stromal Tumors(2013)79 cited
- → Novel pathway in Bcr-Abl signal transduction involves Akt-independent, PLC-γ1-driven activation of mTOR/p70S6-kinase pathway(2009)68 cited