Sydney R. Coffey
Western Washington University(US)
Publications by Year
Research Areas
Genetic Neurodegenerative Diseases, Mitochondrial Function and Pathology, Neuroscience and Neuropharmacology Research, Muscle Physiology and Disorders, RNA Research and Splicing
Most-Cited Works
- → Transcriptional regulatory networks underlying gene expression changes in Huntington's disease(2018)87 cited
- → Single-Nucleus RNA-Seq Reveals Dysregulation of Striatal Cell Identity Due to Huntington's Disease Mutations(2021)74 cited
- → Motivational, proteostatic and transcriptional deficits precede synapse loss, gliosis and neurodegeneration in the B6.HttQ111/+ model of Huntington’s disease(2017)25 cited
- → Early Detection of Apathetic Phenotypes in Huntington’s Disease Knock-in Mice Using Open Source Tools(2018)20 cited
- → Peripheral huntingtin silencing does not ameliorate central signs of disease in the B6.HttQ111/+ mouse model of Huntington’s disease(2017)20 cited
- → Single-nucleus RNA-seq reveals dysregulation of striatal cell identity due to Huntington’s disease mutations(2020)12 cited
- → Huntingtin lowering reduces somatic instability at CAG-expanded loci(2020)10 cited
- → Huntingtin loss in hepatocytes is associated with altered metabolism, adhesion, and liver zonation(2023)8 cited
- → Suppression of Huntington’s Disease Somatic Instability by Transcriptional Repression and Direct CAG Repeat Binding(2024)7 cited
- → Stool is a sensitive and noninvasive source of DNA for monitoring expansion in repeat expansion disease mouse models(2022)6 cited