Robert A. Kumpf
Pfizer (United States)(US)
Publications by Year
Research Areas
Cancer-related gene regulation, Crystallization and Solubility Studies, X-ray Diffraction in Crystallography, Protein Structure and Dynamics, Epigenetics and DNA Methylation
Most-Cited Works
- → A Mechanism for Ion Selectivity in Potassium Channels: Computational Studies of Cation-π Interactions(1993)635 cited
- → Anticancer Chemosensitization and Radiosensitization by the Novel Poly(ADP-ribose) Polymerase-1 Inhibitor AG14361(2004)483 cited
- → Molecular recognition in aqueous media. New binding studies provide further insights into the cation-.pi. interaction and related phenomena(1993)274 cited
- → Novel Tricyclic Poly(ADP-ribose) Polymerase-1 Inhibitors with Potent Anticancer Chemopotentiating Activity: Design, Synthesis, and X-ray Cocrystal Structure(2002)135 cited
- → Optimization of Orally Bioavailable Enhancer of Zeste Homolog 2 (EZH2) Inhibitors Using Ligand and Property-Based Design Strategies: Identification of Development Candidate (R)-5,8-Dichloro-7-(methoxy(oxetan-3-yl)methyl)-2-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3,4-dihydroisoquinolin-1(2H)-one (PF-06821497)(2017)126 cited
- → Design and Synthesis of Pyridone-Containing 3,4-Dihydroisoquinoline-1(2 H )-ones as a Novel Class of Enhancer of Zeste Homolog 2 (EZH2) Inhibitors(2016)68 cited
- → Interaction of formaldehyde with water(1989)49 cited
- → Development of Intergenotypic Chimeric Replicons To Determine the Broad-Spectrum Antiviral Activities of Hepatitis C Virus Polymerase Inhibitors(2008)48 cited
- → Design, Synthesis, and Evaluation of 3,4-Dihydro-2H-[1,4]diazepino[6,7,1-hi]indol-1-ones as Inhibitors of Poly(ADP-Ribose) Polymerase(2004)45 cited
- → Interaction of carbon dioxide and water investigated by a combination of ab initio and SOLDRI-MM2 techniques(1989)30 cited