Jessica E. Young
University of Washington(US)
Publications by Year
Research Areas
Alzheimer's disease research and treatments, Cellular transport and secretion, Neuroinflammation and Neurodegeneration Mechanisms, Pluripotent Stem Cells Research, Cholinesterase and Neurodegenerative Diseases
Most-Cited Works
- → Somatic coding mutations in human induced pluripotent stem cells(2011)1,254 cited
- → Inhibition of Calpain Cleavage of Huntingtin Reduces Toxicity(2004)284 cited
- → Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease(2004)221 cited
- → Elucidating Molecular Phenotypes Caused by the SORL1 Alzheimer’s Disease Genetic Risk Factor Using Human Induced Pluripotent Stem Cells(2015)189 cited
- → The Presenilin-1 ΔE9 Mutation Results in Reduced γ-Secretase Activity, but Not Total Loss of PS1 Function, in Isogenic Human Stem Cells(2013)182 cited
- → Depletion of the AD Risk Gene SORL1 Selectively Impairs Neuronal Endosomal Traffic Independent of Amyloidogenic APP Processing(2020)172 cited
- → Polyglutamine-expanded androgen receptor interferes with TFEB to elicit autophagy defects in SBMA(2014)170 cited
- → Akt blocks ligand binding and protects against expanded polyglutamine androgen receptor toxicity(2007)148 cited
- → Human microglia show unique transcriptional changes in Alzheimer’s disease(2023)140 cited
- → Nutrient Deprivation Induces Neuronal Autophagy and Implicates Reduced Insulin Signaling in Neuroprotective Autophagy Activation(2008)127 cited