Gerhard Gmaschitz
Boehringer Ingelheim (Austria)(AT)
Publications by Year
Research Areas
Peptidase Inhibition and Analysis, Protein Degradation and Inhibitors, Cancer-related Molecular Pathways, Catalytic C–H Functionalization Methods, Click Chemistry and Applications
Most-Cited Works
- → A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo(2022)197 cited
- → Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRAS G12C Inhibitor(2022)75 cited
- → Homo-BacPROTAC-induced degradation of ClpC1 as a strategy against drug-resistant mycobacteria(2024)40 cited
- → Targeted Synthesis of Complex Spiro[3H‐indole‐3,2′‐pyrrolidin]‐2(1H)‐ones by Intramolecular Cyclization of Azomethine Ylides: Highly Potent MDM2–p53 Inhibitors(2018)28 cited
- → Synthesis of MDM2-p53 Inhibitor BI-0282 via a Dipolar Cycloaddition and Late-Stage Davis–Beirut Reaction(2022)5 cited
- → Abstract 4630: Development of selective and potent CDK8 inhibitors that increase NK cell activity, which translates in tumor surveillance(2017)1 cited