a public good project by the
Synthesis
Company
of California

© 2026

Shinji Sakuma | doi.page

0 works0 citations0 h-index

Shinji Sakuma

Publications by Year

Research Areas

Drug Solubulity and Delivery Systems, Advanced Drug Delivery Systems, RNA Interference and Gene Delivery, Drug Transport and Resistance Mechanisms, Glycosylation and Glycoproteins Research

Most-Cited Works

→ Design of nanoparticles composed of graft copolymers for oral peptide delivery(2001)194 cited
→ Site of drug absorption after oral administration: Assessment of membrane permeability and luminal concentration of drugs in each segment of gastrointestinal tract(2006)175 cited
→ Isolation, identification, and biological activities of oxidative metabolites of FK506, a potent immunosuppressive macrolide lactone.(1993)106 cited
→ Further metabolism of FK506 (tacrolimus). Identification and biological activities of the metabolites oxidized at multiple sites of FK506.(1995)104 cited
→ Design of novel bioconjugates for targeted drug delivery(2002)101 cited
→ Effect of Food Intake on the Oral Absorption of Poorly Water-Soluble Drugs: In Vitro Assessment of Drug Dissolution and Permeation Assay System(2006)101 cited

→ Mechanisms of Membrane Transport of Poorly Soluble Drugs: Role of Micelles in Oral Absorption Processes(2009)

99 cited

→ Mucoadhesion of polystyrene nanoparticles having surface hydrophilic polymeric chains in the gastrointestinal tract(1999)89 cited

→ Oral peptide delivery using nanoparticles composed of novel graft copolymers having hydrophobic backbone and hydrophilic branches(1997)87 cited

→ Application of Dissolution/Permeation System for Evaluation of Formulation Effect on Oral Absorption of Poorly Water-Soluble Drugs in Drug Development(2011)84 cited