Erik Wagner
National Institutes of Health(US)National Center for Advancing Translational Sciences(US)
Publications by Year
Research Areas
Alzheimer's disease research and treatments, Cholinesterase and Neurodegenerative Diseases, Chemical Synthesis and Analysis, Computational Drug Discovery Methods, Protein Structure and Dynamics
Most-Cited Works
- → Impact of Apolipoprotein E (ApoE) Polymorphism on Brain ApoE Levels(2008)344 cited
- → Begacestat (GSI-953): A Novel, Selective Thiophene Sulfonamide Inhibitor of Amyloid Precursor Protein γ-Secretase for the Treatment of Alzheimer’s Disease(2009)157 cited
- → Enhanced clearance of Aβ in brain by sustaining the plasmin proteolysis cascade(2008)140 cited
- → Design and Synthesis of 5,5′-Disubstituted Aminohydantoins as Potent and Selective Human β-Secretase (BACE1) Inhibitors(2009)133 cited
- → Aminoimidazoles as Potent and Selective Human β-Secretase (BACE1) Inhibitors(2009)113 cited
- → Discovery of Begacestat, a Notch-1-Sparing γ-Secretase Inhibitor for the Treatment of Alzheimer’s Disease(2008)109 cited
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