Julie A. C. Alexandre
Vertex Pharmaceuticals (United Kingdom)(GB)
Publications by Year
Research Areas
Biochemical and Molecular Research, HIV/AIDS drug development and treatment, Chronic Lymphocytic Leukemia Research, Tryptophan and brain disorders, Peptidase Inhibition and Analysis
Most-Cited Works
- → Novel Antiviral C5-Substituted Pyrimidine Acyclic Nucleoside Phosphonates Selected as Human Thymidylate Kinase Substrates(2010)57 cited
- → New 4‐Amino‐1,2,3‐Triazole Inhibitors of Indoleamine 2,3‐Dioxygenase Form a Long‐Lived Complex with the Enzyme and Display Exquisite Cellular Potency(2017)37 cited
- → Enantioselectivity of human AMP, dTMP and UMP-CMP kinases(2007)18 cited
- → 5′,6′‐Nucleoside Phosphonate Analogues Architecture: Synthesis and Comparative Evaluation towards Metabolic Enzymes(2011)17 cited
- → Nucleotide binding to human UMP‐CMP kinase using fluorescent derivatives − a screening based on affinity for the UMP‐CMP binding site(2007)15 cited
- → Looking for New Pyrimidine Acyclic Nucleotide Analogues Designed for Phosphorylation by Human Ump-Cmp Kinase(2007)1 cited
- → Enantio-Selectivity of Human Nucleoside Monophosphate Kinases(2007)1 cited
- → Evaluation of C-5 Substituted Uracil Acyclic Phosphonates as Substrates or Inhibitors for DTMP and UMP–CMP Kinases and Potential Antipox Derivatives(2008)1 cited
- → Cover Feature: New 4‐Amino‐1,2,3‐Triazole Inhibitors of Indoleamine 2,3‐Dioxygenase Form a Long‐Lived Complex with the Enzyme and Display Exquisite Cellular Potency (ChemBioChem 6/2018)(2018)
- Towards an improved [beta]-1,4-mannosyltransferase for biocatalysis fusions to fluorescent partners and application for the development of high throughput assays(2005)