Robert A. Mack

Publications by Year

Research Areas

Synthesis and Biological Evaluation, Synthesis of Organic Compounds, Organic Chemistry Synthesis Methods, Cyclopropane Reaction Mechanisms, Receptor Mechanisms and Signaling

Most-Cited Works

• → The 5-HT3 antagonist tropisetron (ICS 205-930) is a potent and selective α7 nicotinic receptor partial agonist(2001)158 cited
• → (−)-Spiro[1-azabicyclo[2.2.2]octane-3,5‘-oxazolidin-2‘-one], a Conformationally Restricted Analogue of Acetylcholine, Is a Highly Selective Full Agonist at the α7 Nicotinic Acetylcholine Receptor(2000)132 cited
• → Synthesis and Use of 5-Vinyl-1,2,4-oxadiazoles as Michael Acceptors. A Rapid Synthesis of the Potent Muscarinic Agonist L-670,548(1996)48 cited
• → Drug-induced modifications of the immune response. 12. 4,5-Dihydro-4-oxo-2-(substituted amino)-3-furancarboxylic acids and derivatives as novel antiallergic agents(1988)46 cited
• → A Chiral Synthesis of (−)-Spiro[1-azabicyclo[2.2.2]octane-3,5‘- oxazolidin-2‘-one]: A Conformationally Restricted Analogue of Acetylcholine That Is a Potent and Selective α7 Nicotinic Receptor Agonist(2004)28 cited
• → Drug‐induced modifications of the immune response part 94‐(Arylamino)‐2,5‐dihydro‐2‐oxo‐N‐(trans‐2‐phenylcycolopropyl)furan‐3‐carboxamides as Novel Antiallergic Compounds(1987)9 cited
• → A novel 3(2H)-furanone-2(5H)-furanone rearrangement(1987)9 cited
• → Synthesis of some novel 1,3-dihydro-2H-benzimidazol-2-ylidenes(1993)8 cited
• → Synthesis of Substituted 4,5-Dihydro-4-oxo-2-[(2-trans-phenylcyclopropyl)amino]-3-furancarboxylic Acids and Ethyl Esters(1986)7 cited
• → Synthesis and biological activity of enantiomers of a conformationally restricted muscarone analog(1995)6 cited