Tieguang Yao
Publications by Year
Research Areas
Cancer-related Molecular Pathways, Cancer therapeutics and mechanisms, Synthesis and Properties of Aromatic Compounds, Advanced Breast Cancer Therapies, Supramolecular Chemistry and Complexes
Most-Cited Works
- → Cyclophanes containing large polycyclic aromatic hydrocarbons(2015)166 cited
- → Discovery of 5-{4-[(7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl}-N-methylpyridine-2-carboxamide (AZD5305): A PARP1–DNA Trapper with High Selectivity for PARP1 over PARP2 and Other PARPs(2021)131 cited
- → Discovery of AZD4573, a Potent and Selective Inhibitor of CDK9 That Enables Short Duration of Target Engagement for the Treatment of Hematological Malignancies(2020)100 cited
- → Nonplanar aromatic compounds. Part 10: A strategy for the synthesis of aromatic belts-all wrapped up or down the tubes?(2008)54 cited
- → Structure‐Based Design of Selective Noncovalent CDK12 Inhibitors(2017)52 cited
- → Potent and Selective Inhibitors of the Epidermal Growth Factor Receptor to Overcome C797S-Mediated Resistance(2021)31 cited
- → Discovery of a Series of 7-Azaindoles as Potent and Highly Selective CDK9 Inhibitors for Transient Target Engagement(2021)24 cited
- → Discovery of 6-Fluoro-5-{4-[(5-fluoro-2-methyl-3-oxo-3,4-dihydroquinoxalin-6-yl)methyl]piperazin-1-yl}-N-methylpyridine-2-carboxamide (AZD9574): A CNS-Penetrant, PARP1-Selective Inhibitor(2024)23 cited
- → Discovery and Optimization of Pyrazine Carboxamide AZ3246, a Selective HPK1 Inhibitor(2025)16 cited
- → Discovery of AZD8421: A Potent CDK2 Inhibitor with Selectivity Against Other CDK Family Members and the Human Kinome(2025)3 cited