Mark Wigglesworth
Publications by Year
Research Areas
Receptor Mechanisms and Signaling, Neuropeptides and Animal Physiology, Computational Drug Discovery Methods, CRISPR and Genetic Engineering, Viral Infectious Diseases and Gene Expression in Insects
Most-Cited Works
- → The Orphan G Protein-coupled Receptors GPR41 and GPR43 Are Activated by Propionate and Other Short Chain Carboxylic Acids(2003)2,311 cited
- → Engineering a Model Cell for Rational Tuning of GPCR Signaling(2019)227 cited
- → Screening β-Arrestin Recruitment for the Identification of Natural Ligands for Orphan G-Protein–Coupled Receptors(2013)178 cited
- → Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides(2018)129 cited
- → Identification of a novel asthma susceptibility gene on chromosome 1qter and its functional evaluation(2008)67 cited
- → Understanding Cytotoxicity and Cytostaticity in a High-Throughput Screening Collection(2016)44 cited
- → Non-peptidic antagonists of the CGRP receptor, BIBN4096BS and MK-0974, interact with the calcitonin receptor-like receptor via methionine-42 and RAMP1 via tryptophan-74(2009)41 cited
- → A Perspective on Synthetic Biology in Drug Discovery and Development—Current Impact and Future Opportunities(2021)40 cited
- → Discovery and Optimization of Allosteric Inhibitors of Mutant Isocitrate Dehydrogenase 1 (R132H IDH1) Displaying Activity in Human Acute Myeloid Leukemia Cells(2016)38 cited
- → Increasing the delivery of next generation therapeutics from high throughput screening libraries(2015)34 cited