J. Patrick McGovren
Pfizer (United States)(US)
Publications by Year
Research Areas
Cancer therapeutics and mechanisms, Cancer Treatment and Pharmacology, Synthesis and Biological Evaluation, Pharmacogenetics and Drug Metabolism, DNA and Nucleic Acid Chemistry
Most-Cited Works
- → Didemnins: Antiviral and Antitumor Depsipeptides from a Caribbean Tunicate(1981)310 cited
- → Mode of action of bullatacin: A potent antitumor and pesticidal Annonaceous acetogenin(1993)186 cited
- → Preliminary toxicity studies with the DNA-binding antibiotic, CC-1065.(1984)144 cited
- → Molecular basis for sequence-specific DNA alkylation by CC-1065(1988)143 cited
- → CC-1065(NSC 298223), a potent new antitumor agent. Improved production and isolation, characterization and antitumor activity.(1981)140 cited
- → Stereoelectronic factors influencing the biological activity and DNA interaction of synthetic antitumor agents modeled on CC-1065(1988)129 cited
- → The chemistry, mechanism of action and biological properties of CC-1065, a potent antitumor antibiotic.(1986)116 cited
- → Sequence specificity of DNA alkylation by the unnatural enantiomer of CC-1065 and its synthetic analogs(1990)106 cited
- Cytotoxicity and antitumor activity of carzelesin, a prodrug cyclopropylpyrroloindole analogue.(1992)
- → Adozelesin, a selected lead among cyclopropylpyrroloindole analogs of the DNA-binding antibiotic, CC-1065(1991)84 cited