Travis Stams
Novartis (United States)(US)
Publications by Year
Research Areas
Protein Tyrosine Phosphatases, Galectins and Cancer Biology, Wnt/β-catenin signaling in development and cancer, Bioactive Compounds and Antitumor Agents, Pancreatic function and diabetes
Most-Cited Works
- → Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases(2016)909 cited
- → Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor(2016)286 cited
- → Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer(2020)210 cited
- → Protein component of the ribozyme ribonuclease P alters substrate recognition by directly contacting precursor tRNA(1998)163 cited
- → Structural reorganization of SHP2 by oncogenic mutations and implications for oncoprotein resistance to allosteric inhibition(2018)163 cited
- → Structure of human neutrophil collagenase reveals large S1′ specificity pocket(1994)162 cited
- → Human HDAC isoform selectivity achieved via exploitation of the acetate release channel with structurally unique small molecule inhibitors(2011)153 cited
- → Ribonuclease P Protein Structure: Evolutionary Origins in the Translational Apparatus(1998)153 cited
- → Crystal structure of the secretory form of membrane-associated human carbonic anhydrase IV at 2.8-Å resolution(1996)144 cited
- → Dual Allosteric Inhibition of SHP2 Phosphatase(2018)127 cited