Barry S. Orlek
University of Leeds(GB)GlaxoSmithKline (United Kingdom)(GB)
Publications by Year
Research Areas
Chemical Synthesis and Analysis, Synthesis and Biological Evaluation, Receptor Mechanisms and Signaling, Asymmetric Synthesis and Catalysis, Click Chemistry and Applications
Most-Cited Works
- → Comparison of azabicyclic esters and oxadiazoles as ligands for the muscarinic receptor(1991)204 cited
- → Penicillinase active sites: Labelling of serine‐44 in β‐lactamase I by 6β‐bromopenicillanic acid(1979)129 cited
- → Synthesis and muscarinic activities of quinuclidin-3-yltriazole and -tetrazole derivatives(1992)83 cited
- → Substituent variation in azabicyclic triazole- and tetrazole-based muscarinic receptor ligands(1992)73 cited
- → 6 β-Bromopenicillanic acid inactivates β-lactamase I(1979)73 cited
- → Structurally novel histamine H3 receptor antagonists GSK207040 and GSK334429 improve scopolamine-induced memory impairment and capsaicin-induced secondary allodynia in rats(2007)64 cited
- → Lipopeptide substrates for SpsB, the Staphylococcus aureus type I signal peptidase: design, conformation and conversion to α-ketoamide inhibitors(2003)52 cited
- → SB 202026: A Novel Muscarinic Partial Agonist with Functional Selectivity for M1 Receptors(1997)47 cited
- → Kinetics of inactivation of β-lactamase I by 6 β-bromopenicillanic acid(1980)35 cited
- → Stereoselective synthesis of protected amines and diamines from alkenes using N,N-Dichloro-t-butylcarbamate(1991)34 cited