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Dana Gitnick

Publications by Year

Research Areas

Melanoma and MAPK Pathways, Synthesis and biological activity, Cytokine Signaling Pathways and Interactions, Cancer Mechanisms and Therapy, Microtubule and mitosis dynamics

Most-Cited Works

→ Identification of 1-(3-(6,7-Dimethoxyquinazolin-4-yloxy)phenyl)-3-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)urea Hydrochloride (CEP-32496), a Highly Potent and Orally Efficacious Inhibitor of V-RAF Murine Sarcoma Viral Oncogene Homologue B1 (BRAF) V600E(2011)58 cited
→ CEP-32496: A Novel Orally Active BRAFV600E Inhibitor with Selective Cellular and In Vivo Antitumor Activity(2012)47 cited
→ Discovery and optimization of a highly efficacious class of 5-aryl-2-aminopyridines as FMS-like tyrosine kinase 3 (FLT3) inhibitors(2015)18 cited
→ Novel series of pyrrolotriazine analogs as highly potent pan-Aurora kinase inhibitors(2011)17 cited
→ 4-Quinazolinyloxy-diaryl ureas as novel BRAFV600E inhibitors(2011)13 cited
→ Discovery of AC710, a Globally Selective Inhibitor of Platelet-Derived Growth Factor Receptor-Family Kinases(2012)10 cited
→ Discovery of Highly Potent and Selective Pan-Aurora Kinase Inhibitors with Enhanced in Vivo Antitumor Therapeutic Index(2012)10 cited
→ Supplementary Data 1 from CEP-32496: A Novel Orally Active BRAFV600E Inhibitor with Selective Cellular and In Vivo Antitumor Activity(2023)
→ Data from CEP-32496: A Novel Orally Active BRAFV600E Inhibitor with Selective Cellular and In Vivo Antitumor Activity(2023)