Yunsheng Hsieh
Chung Shan Medical University(TW)
Publications by Year
Research Areas
Computational Drug Discovery Methods, Protein Structure and Dynamics, Ubiquitin and proteasome pathways, Analytical Chemistry and Chromatography, Mass Spectrometry Techniques and Applications
Most-Cited Works
- → Direct analysis of drug candidates in tissue by matrix‐assisted laser desorption/ionization mass spectrometry(2003)360 cited
- → Investigation of matrix effects in bioanalytical high‐performance liquid chromatography/tandem mass spectrometric assays: application to drug discovery(2002)343 cited
- → Discovery of (1 R ,5 S )- N -[3-Amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]- 3-[2( S )-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2( S )-carboxamide (SCH 503034), a Selective, Potent, Orally Bioavailable Hepatitis C Virus NS3 Protease Inhibitor: A Potential Therapeutic Agent for the Treatment of Hepatitis C Infection(2006)278 cited
- → Discovery of a Novel, Orally Active Himbacine-Based Thrombin Receptor Antagonist (SCH 530348) with Potent Antiplatelet Activity(2008)267 cited
- → Matrix‐assisted laser desorption/ionization imaging mass spectrometry for direct measurement of clozapine in rat brain tissue(2006)182 cited
- → Targeting the Replication Checkpoint Using SCH 900776, a Potent and Functionally Selective CHK1 Inhibitor Identified via High Content Screening(2011)171 cited
- → Cassette‐accelerated rapid rat screen: a systematic procedure for the dosing and liquid chromatography/atmospheric pressure ionization tandem mass spectrometric analysis of new chemical entities as part of new drug discovery(2001)151 cited
- → Catalytic Properties of Human Manganese Superoxide Dismutase(1996)141 cited
- → Mapping pharmaceuticals in tissues using MALDI imaging mass spectrometry(2006)139 cited
- → Quantitative screening and matrix effect studies of drug discovery compounds in monkey plasma using fast‐gradient liquid chromatography/tandem mass spectrometry(2001)135 cited