Doug Marcotte
Publications by Year
Research Areas
Protein Kinase Regulation and GTPase Signaling, Synthesis and biological activity, Melanoma and MAPK Pathways, Cancer Mechanisms and Therapy, Computational Drug Discovery Methods
Most-Cited Works
- → Discovery and Characterization of Non-ATP Site Inhibitors of the Mitogen Activated Protein (MAP) Kinases(2010)80 cited
- → ATP-Competitive MLKL Binders Have No Functional Impact on Necroptosis(2016)38 cited
- → Structure-based design of low-nanomolar PIM kinase inhibitors(2014)24 cited
- → Enabling structure-based drug design of Tyk2 through co-crystallization with a stabilizing aminoindazole inhibitor(2012)16 cited
- → Design, synthesis, and biological evaluation of pyrazolopyrimidine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (part I)(2011)10 cited
- → The 1.6 A crystal structure of human bruton's tyrosine kinase bound to a pyrrolopyrimidine-containing compound(2009)1 cited
- → GLK co-crystal structure with aminopyrrolopyrimidine inhibitor(2016)
- → KEAP1 Kelch domain in complex with Compound 2(2019)
- → p38-alpha complexed with Compound 10(2010)
- → Crystal structure of PICK1 in complex with the small molecule inhibitor 1o(2017)