Neil Pegg
CellCentric (United Kingdom)(GB)
Publications by Year
Research Areas
Protein Degradation and Inhibitors, Prostate Cancer Treatment and Research, Multiple Myeloma Research and Treatments, Chemical Synthesis and Analysis, Ubiquitin and proteasome pathways
Most-Cited Works
- → Targeting the p300/CBP Axis in Lethal Prostate Cancer(2021)271 cited
- → Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies(2023)100 cited
- → Discovery of Novel PI3-Kinase δ Specific Inhibitors for the Treatment of Rheumatoid Arthritis: Taming CYP3A4 Time-Dependent Inhibition(2012)66 cited
- → [3.3] Sigmatropy within 1-vinyl-2-alkenyl-7,7-dimethyl-exo-norbornan-2-ols. The first atropselective oxyanionic Cope rearrangement(1990)60 cited
- → Potent and selective inhibitors of PI3Kδ: Obtaining isoform selectivity from the affinity pocket and tryptophan shelf(2012)50 cited
- → Identification of 2,3-diaryl-pyrazolo[1,5-b]pyridazines as potent and selective cyclooxygenase-2 inhibitors(2004)46 cited
- → Tetrazole NK1 receptor antagonists: The identification of an exceptionally potent orally active antiemetic compound(1996)43 cited
- → Direct oxygenation of enolates generated by anionic oxy-Cope rearrangement. Expedient preparation of polycyclic .alpha.-hydroxy ketones(1989)43 cited
- → The synthesis of a conformationally restrained, combined thromboxane antagonist / synthase inhibitor using an intramolecular ‘Stille’- or ‘Grigg’-palladium-catalysed cyclisation strategy(1993)38 cited
- → 3-substituted-1,2,4-oxadiazolin-5-one; A useful amidine precursor and protecting group(1995)36 cited