Lora K. Picton
Howard Hughes Medical Institute(US)Stanford University(US)
Publications by Year
Research Areas
Immune Cell Function and Interaction, T-cell and B-cell Immunology, CAR-T cell therapy research, Mitochondrial Function and Pathology, Immunotherapy and Immune Responses
Most-Cited Works
- → The Putative Drp1 Inhibitor mdivi-1 Is a Reversible Mitochondrial Complex I Inhibitor that Modulates Reactive Oxygen Species(2017)572 cited
- → Design of protein-binding proteins from the target structure alone(2022)534 cited
- → Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes(2018)357 cited
- → Alternative evolutionary histories in the sequence space of an ancient protein(2017)229 cited
- → An engineered IL-2 partial agonist promotes CD8+ T cell stemness(2021)171 cited
- → A human orthogonal IL-2 and IL-2Rβ system enhances CAR T cell expansion and antitumor activity in a murine model of leukemia(2021)132 cited
- → Immune receptor inhibition through enforced phosphatase recruitment(2020)120 cited
- → Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposure(2023)111 cited
- → Potentiating adoptive cell therapy using synthetic IL-9 receptors(2022)109 cited
- → Facile discovery of surrogate cytokine agonists(2022)74 cited