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Marion S. Helfand | doi.page

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Marion S. Helfand

Scuola Internazionale Superiore di Studi Avanzati(IT)Louis Stokes Cleveland VA Medical Center(US)

Publications by Year

Research Areas

Antibiotic Resistance in Bacteria, Antibiotics Pharmacokinetics and Efficacy, Antimicrobial Resistance in Staphylococcus, Clostridium difficile and Clostridium perfringens research, Vibrio bacteria research studies

Most-Cited Works

→ Identification of a New Allelic Variant of theAcinetobacter baumanniiCephalosporinase, ADC-7 β-Lactamase: Defining a Unique Family of Class C Enzymes(2005)146 cited
→ &#946;-Lactamases: A Survey of Protein Diversity(2003)83 cited
→ β‐Lactam Antibiotics and Gastrointestinal Colonization with Vancomycin‐Resistant Enterococci(2004)82 cited
→ High Resolution Crystal Structures of the trans-Enamine Intermediates Formed by Sulbactam and Clavulanic Acid and E166A SHV-1 β-Lactamase(2005)72 cited
→ Clavulanic Acid Inactivation of SHV-1 and the Inhibitor-resistant S130G SHV-1 β-Lactamase(2005)70 cited
→ Tazobactam Forms a Stoichiometric trans-Enamine Intermediate in the E166A Variant of SHV-1 β-Lactamase: 1.63 Å Crystal Structure,(2004)69 cited

→ Understanding Resistance to β-Lactams and β-Lactamase Inhibitors in the SHV β-Lactamase(2003)

67 cited

→ Following the Reactions of Mechanism-Based Inhibitors with β-Lactamase by Raman Crystallography(2003)67 cited

→ Mechanisms by Which Anaerobic Microbiota Inhibit the Establishment in Mice of Intestinal Colonization by Vancomycin‐ResistantEnterococcus(2005)66 cited

→ Rational Design of a β-Lactamase Inhibitor Achieved via Stabilization of the trans-Enamine Intermediate: 1.28 Å Crystal Structure of wt SHV-1 Complex with a Penam Sulfone(2006)54 cited