Christopher L. McClendon
Pfizer (United States)(US)
Publications by Year
Research Areas
Protein Structure and Dynamics, Enzyme Structure and Function, Protein Kinase Regulation and GTPase Signaling, Computational Drug Discovery Methods, RNA and protein synthesis mechanisms
Most-Cited Works
- → Reaching for high-hanging fruit in drug discovery at protein–protein interfaces(2007)1,937 cited
- → Dynamic architecture of a protein kinase(2014)263 cited
- → Quantifying Correlations Between Allosteric Sites in Thermodynamic Ensembles(2009)235 cited
- → Turning a protein kinase on or off from a single allosteric site via disulfide trapping(2011)156 cited
- → A dynamic hydrophobic core orchestrates allostery in protein kinases(2017)113 cited
- → Comparing Conformational Ensembles Using the Kullback–Leibler Divergence Expansion(2012)93 cited
- → Modeling Conformational Ensembles of Slow Functional Motions in Pin1-WW(2010)90 cited
- → Synchronous Opening and Closing Motions Are Essential for cAMP-Dependent Protein Kinase A Signaling(2014)64 cited
- → Mutation of a kinase allosteric node uncouples dynamics linked to phosphotransfer(2017)60 cited
- → Decoding the Interactions Regulating the Active State Mechanics of Eukaryotic Protein Kinases(2016)54 cited