Marcella Brescia
Leiden University Medical Center(NL)
Publications by Year
Research Areas
Pluripotent Stem Cells Research, Phosphodiesterase function and regulation, Receptor Mechanisms and Signaling, CRISPR and Genetic Engineering, Cardiac electrophysiology and arrhythmias
Most-Cited Works
- → FRET biosensor uncovers cAMP nano-domains at β-adrenergic targets that dictate precise tuning of cardiac contractility(2017)213 cited
- → An essential cell-autonomous role for hepcidin in cardiac iron homeostasis(2016)182 cited
- → Modulation of Compartmentalised Cyclic Nucleotide Signalling via Local Inhibition of Phosphodiesterase Activity(2016)56 cited
- → Vascularized hiPSC-derived 3D cardiac microtissue on chip(2023)54 cited
- → Expanding the editable genome and CRISPR–Cas9 versatility using DNA cutting-free gene targeting based on in trans paired nicking(2019)35 cited
- → Phosphodiesterase 2A as a therapeutic target to restore cardiac neurotransmission during sympathetic hyperactivity(2018)30 cited
- → High-Capacity Adenoviral Vectors Permit Robust and Versatile Testing of DMD Gene Repair Tools and Strategies in Human Cells(2020)24 cited
- → Large-scale genome editing based on high-capacity adenovectors and CRISPR-Cas9 nucleases rescues full-length dystrophin synthesis in DMD muscle cells(2022)19 cited
- → Multi-Compartment, Early Disruption of cGMP and cAMP Signalling in Cardiac Myocytes from the mdx Model of Duchenne Muscular Dystrophy(2020)15 cited
- → Adenoviral Transduction of FRET-Based Biosensors for cAMP in Primary Adult Mouse Cardiomyocytes(2015)14 cited