a public good project by the
Synthesis
Company
of California

© 2026

E. Jon Jacobsen | doi.page

0 works0 citations0 h-index

E. Jon Jacobsen

Confluence Life Sciences (United States)(US)

Publications by Year

Research Areas

Nicotinic Acetylcholine Receptors Study, Asymmetric Synthesis and Catalysis, Chemical synthesis and alkaloids, Phenothiazines and Benzothiazines Synthesis and Activities, Neuroscience and Neuropharmacology Research

Most-Cited Works

→ Novel 21-amino steroids as potent inhibitors of iron-dependent lipid peroxidation.(1987)469 cited
→ Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with CP-690550 and CMP-6(2010)224 cited
→ Salen-Manganese Complexes Are Superoxide Dismutase-Mimics(1993)208 cited
→ Discovery ofN-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, an Agonist of the α7 Nicotinic Acetylcholine Receptor, for the Potential Treatment of Cognitive Deficits in Schizophrenia: Synthesis and Structure−Activity Relationship(2006)189 cited
→ U-78517F: a potent inhibitor of lipid peroxidation with activity in experimental brain injury and ischemia.(1991)152 cited
→ The 21-aminosteroids: Potent inhibitors of lipid peroxidation for the treatment of central nervous system trauma and ischemia(1989)128 cited

→ The Hepatitis B Virus Ribonuclease H Is Sensitive to Inhibitors of the Human Immunodeficiency Virus Ribonuclease H and Integrase Enzymes(2013)109 cited

→ Selective inhibition of the p38α MAPK–MK2 axis inhibits inflammatory cues including inflammasome priming signals(2018)98 cited

→ Design, synthesis, structure–activity relationship, and in vivo activity of azabicyclic aryl amides as α7 nicotinic acetylcholine receptor agonists(2006)94 cited

→ 3-Phenyl-Substituted Imidazo[1,5-a]quinoxalin-4-ones and Imidazo[1,5-a]quinoxaline Ureas That Have High Affinity at the GABA_A/Benzodiazepine Receptor Complex(1996)91 cited