Mario Cardozo
Nurix (United States)(US)
Publications by Year
Research Areas
Computational Drug Discovery Methods, Chemical Synthesis and Analysis, PI3K/AKT/mTOR signaling in cancer, Cytokine Signaling Pathways and Interactions, Biochemical and Molecular Research
Most-Cited Works
- → AMG 176, a Selective MCL1 Inhibitor, Is Effective in Hematologic Cancer Models Alone and in Combination with Established Therapies(2018)409 cited
- → Structure-Guided Design, Synthesis, and Evaluation of Guanine-Derived Inhibitors of the eIF4E mRNA–Cap Interaction(2012)220 cited
- → MM-GB/SA Rescoring of Docking Poses in Structure-Based Lead Optimization(2008)215 cited
- → Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction(2019)203 cited
- → Identification and Functional Characterization of Allosteric Agonists for the G Protein-Coupled Receptor FFA2(2008)154 cited
- → Binding Site Elucidation of Hydantoin-Based Antagonists of LFA-1 Using Multidisciplinary Technologies: Evidence for the Allosteric Inhibition of a Protein−Protein Interaction(2001)131 cited
- → Trifluoromethyl group as a pharmacophore: Effect of replacing a CF3 group on binding and agonist activity of a glucocorticoid receptor ligand(2005)106 cited
- → Structure guided design of a series of sphingosine kinase (SphK) inhibitors(2013)98 cited
- → Discovery of IPN60090, a Clinical Stage Selective Glutaminase-1 (GLS-1) Inhibitor with Excellent Pharmacokinetic and Physicochemical Properties(2020)89 cited
- → Discovery and in Vivo Evaluation of (S)-N-(1-(7-Fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine (AMG319) and Related PI3Kδ Inhibitors for Inflammation and Autoimmune Disease(2014)85 cited