Gérald Gavory
Almac (United Kingdom)(GB)
Publications by Year
Research Areas
Ubiquitin and proteasome pathways, Cancer-related Molecular Pathways, Protein Degradation and Inhibitors, Microtubule and mitosis dynamics, RNA Interference and Gene Delivery
Most-Cited Works
- → Discovery and characterization of highly potent and selective allosteric USP7 inhibitors(2017)219 cited
- → Identification and Characterization of Dual Inhibitors of the USP25/28 Deubiquitinating Enzyme Subfamily(2017)85 cited
- → Identification and Structure-Guided Development of Pyrimidinone Based USP7 Inhibitors(2018)66 cited
- → Inhibition of Human Telomerase Activity by an Engineered Zinc Finger Protein that Binds G-Quadruplexes(2004)44 cited
- → Minimum length requirement of the alignment domain of human telomerase RNA to sustain catalytic activity in vitro(2002)38 cited
- → Site-specific cleavage of human telomerase RNA using PNA-neocuproine·Zn(ii) derivatives(2002)29 cited
- → Targeting the single-strand G-rich overhang of telomeres with PNA inhibits cell growth and induces apoptosis of human immortal cells(2004)25 cited
- → Structural Analysis of the Catalytic Core of Human Telomerase RNA by FRET and Molecular Modeling,(2006)24 cited
- → Abstract 3929: Identification of MRT-2359 a potent, selective and orally bioavailable GSPT1-directed molecular glue degrader (MGD) for the treatment of cancers with Myc-induced translational addiction(2022)23 cited
- → Abstract 3449: Development of MRT-2359, an orally bioavailable GSPT1 molecular glue degrader, for the treatment of lung cancers with MYC-induced translational addiction(2023)14 cited