Shinya Mimasu
Astellas Pharma (Japan)(JP)
Publications by Year
Research Areas
Lung Cancer Treatments and Mutations, Quinazolinone synthesis and applications, HER2/EGFR in Cancer Research, Epigenetics and DNA Methylation, Chemical Synthesis and Analysis
Most-Cited Works
- → FAD-dependent lysine-specific demethylase-1 regulates cellular energy expenditure(2012)231 cited
- → Structurally Designed trans-2-Phenylcyclopropylamine Derivatives Potently Inhibit Histone Demethylase LSD1/KDM1,,(2010)173 cited
- → Crystal structure of histone demethylase LSD1 and tranylcypromine at 2.25 Å(2007)131 cited
- → Crystallographic Study of a Site-Specifically Cross-Linked Protein Complex with a Genetically Incorporated Photoreactive Amino Acid,(2010)60 cited
- → Pharmacological and Structural Characterizations of Naquotinib, a Novel Third-Generation EGFR Tyrosine Kinase Inhibitor, in EGFR -Mutated Non–Small Cell Lung Cancer(2018)39 cited
- → High-throughput analysis system of interaction kinetics for data-driven antibody design(2023)15 cited
- → Abstract 2586: ASP8273 selectively inhibits mutant EGFR signal pathway and induces tumor shrinkage in EGFR mutated tumor models(2015)9 cited
- → Full-length in meso structure and mechanism of rat kynurenine 3-monooxygenase inhibition(2021)7 cited
- → Discovery and Biological Evaluation of Potent and Orally Active Human 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors for the Treatment of Type 2 Diabetes Mellitus(2019)5 cited
- → Data from Pharmacological and Structural Characterizations of Naquotinib, a Novel Third-Generation EGFR Tyrosine Kinase Inhibitor, in <i>EGFR</i>-Mutated Non–Small Cell Lung Cancer(2023)1 cited