Longchuan Bai
Dalian Ocean University(CN)University of Michigan(US)University of Michigan–Ann Arbor(US)Michigan Medicine(US)Chinese Academy of Fishery Sciences(CN)
Publications by Year
Research Areas
Protein Degradation and Inhibitors, Ubiquitin and proteasome pathways, Cell death mechanisms and regulation, Multiple Myeloma Research and Treatments, Cancer-related Molecular Pathways
Most-Cited Works
- → A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo(2019)589 cited
- → Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression(2017)356 cited
- → SAR405838: An Optimized Inhibitor of MDM2–p53 Interaction That Induces Complete and Durable Tumor Regression(2014)336 cited
- → Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression(2018)261 cited
- → Structure-Based Discovery of SD-36 as a Potent, Selective, and Efficacious PROTAC Degrader of STAT3 Protein(2019)205 cited
- → Small-molecule SMAC mimetics as new cancer therapeutics