Timothy A. Subashi
Pfizer (United States)(US)
Publications by Year
Research Areas
Drug Transport and Resistance Mechanisms, Epigenetics and DNA Methylation, RNA and protein synthesis mechanisms, Amino Acid Enzymes and Metabolism, Protein Structure and Dynamics
Most-Cited Works
- → Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia(2007)434 cited
- → Crystal structure of cholesteryl ester transfer protein reveals a long tunnel and four bound lipid molecules(2007)271 cited
- → Structural Basis for AMPK Activation: Natural and Synthetic Ligands Regulate Kinase Activity from Opposite Poles by Different Molecular Mechanisms(2014)179 cited
- → Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay(2017)159 cited
- → Pharmacologic Inhibition of Site 1 Protease Activity Inhibits Sterol Regulatory Element-Binding Protein Processing and Reduces Lipogenic Enzyme Gene Expression and Lipid Synthesis in Cultured Cells and Experimental Animals(2008)146 cited
- → CP-225,917 and CP-263,114, Novel Ras Farnesylation Inhibitors from an Unidentified Fungus. I. Taxonomy, Fermentation, Isolation, and Biochemical Properties.(1997)116 cited
- → Glycomimetic Ligands for the Human Asialoglycoprotein Receptor(2012)105 cited
- → X-Ray Crystallographic and Kinetic Studies of Human Sorbitol Dehydrogenase(2003)98 cited
- → Cryo-EM structures of the human glutamine transporter SLC1A5 (ASCT2) in the outward-facing conformation(2019)76 cited
- → Discovery of Fragment-Derived Small Molecules for in Vivo Inhibition of Ketohexokinase (KHK)(2017)49 cited