H. Piechuta
Merck Canada Inc. (Canada)(CA)
Publications by Year
Research Areas
Asthma and respiratory diseases, Synthesis and Reactions of Organic Compounds, Respiratory and Cough-Related Research, Allergic Rhinitis and Sensitization, Synthesis of Organic Compounds
Most-Cited Works
- → L-663,536 (MK-886) (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2-dimethylpropanoic acid), a novel, orally active leukotriene biosynthesis inhibitor(1989)328 cited
- → Pharmacology of MK-0591 (3-[1-(4-chlorobenzyl)-3-(t-butylthio)-5-(quinolin-2-yl-methoxy)-indol-2-yl]-2,2-dimethyl propanoic acid), a potent, orally active leukotriene biosynthesis inhibitor(1992)113 cited
- → Discovery of MK-0476, a potent and orally active leukotriene D4 receptor antagonist devoid of peroxisomal enxyme induction(1995)100 cited
- → Differing mechanisms for leukotriene D4-induced bronchoconstriction in guinea pigs following intravenous and aerosol administration(1982)70 cited
- → L-649,923, Sodium (βS*, γR*)-4-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)-propylthio)-γ-hydroxy-β-methylbenzenebutanoate, a selective, orally active leukotriene receptor antagonist(1986)63 cited
- → Discovery of L-791,943: A potent, selective, non emetic and orally active phosphodiesterase-4 inhibitor(2002)56 cited
- → The activity of synthetic leukotriene C-1 on guinea pig trachea and ileum(1980)47 cited
- → L-648,051, sodium 4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)-propylsulfonyl]-γ-oxo-benzenebutanoate: a leukotriene D4 receptor antagonist(1986)37 cited
- The respiratory response of sensitized rats to challenge with antigen aerosols.(1979)
- → Substituted (Pyridylmethoxy)naphthalenes as Potent and Orally Active 5-Lipoxygenase Inhibitors: Synthesis, Biological Profile, and Pharmacokinetics of L-739,010(1997)29 cited