Clarissa G. Jakob
AbbVie (United States)(US)
Publications by Year
Research Areas
Epigenetics and DNA Methylation, Enzyme Structure and Function, Biochemical and Molecular Research, Cancer-related gene regulation, Synthesis and biological activity
Most-Cited Works
- → Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours(2017)825 cited
- → The Three-dimensional Structures of Antagonistic and Agonistic Forms of the Glucocorticoid Receptor Ligand-binding Domain(2003)337 cited
- → The EED protein–protein interaction inhibitor A-395 inactivates the PRC2 complex(2017)232 cited
- → The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity(2017)128 cited
- → Crystal Structure and Mutagenic Analysis of the Inhibitor-of-Apoptosis Protein Survivin(2000)126 cited
- → X-ray crystallographic structure of ABT-378 (Lopinavir) bound to HIV-1 protease(2002)99 cited
- → Liver-Selective Glucocorticoid Antagonists: A Novel Treatment for Type 2 Diabetes(2004)71 cited
- → Discovery of Potent Inhibitors of Dihydroneopterin Aldolase Using CrystaLEAD High-Throughput X-ray Crystallographic Screening and Structure-Directed Lead Optimization(2004)70 cited
- → Structure reveals function of the dual variable domain immunoglobulin (DVD-Ig™) molecule(2013)66 cited
- → Discovery of A-893, A New Cell-Active Benzoxazinone Inhibitor of Lysine Methyltransferase SMYD2(2015)65 cited