Donna Carr
Publications by Year
Research Areas
Melanoma and MAPK Pathways, Synthesis and biological activity, Protein Kinase Regulation and GTPase Signaling, Cancer Mechanisms and Therapy, Hepatitis C virus research
Most-Cited Works
- → Discovery of a Novel ERK Inhibitor with Activity in Models of Acquired Resistance to BRAF and MEK Inhibitors(2013)676 cited
- → Selective small-molecule inhibition of an RNA structural element(2015)415 cited
- → Farnesyl Transferase Inhibitors Block the Farnesylation of CENP-E and CENP-F and Alter the Association of CENP-E with the Microtubules(2000)320 cited
- → Characterization of Ha-Ras, N-Ras, Ki-Ras4A, and Ki-Ras4B as in Vitro Substrates for Farnesyl Protein Transferase and Geranylgeranyl Protein Transferase Type I(1997)202 cited
- → Crystal Structures of MEK1 Binary and Ternary Complexes with Nucleotides and Inhibitors(2009)176 cited
- → Novel Tricyclic Inhibitors of Farnesyl Protein Transferase(1995)155 cited
- → Development of MK-8353, an orally administered ERK1/2 inhibitor, in patients with advanced solid tumors(2018)146 cited
- → Ras oncoprotein inhibitors: The discovery of potent, ras nucleotide exchange inhibitors and the structural determination of a drug-protein complex(1997)121 cited
- → The Farnesyl Transferase Inhibitor SCH 66336 Induces a G2 → M or G1 Pause in Sensitive Human Tumor Cell Lines(2001)111 cited
- → Exploring the Pharmacokinetic/Pharmacodynamic Relationship of Relebactam (MK-7655) in Combination with Imipenem in a Hollow-Fiber Infection Model(2018)61 cited