Herman D. Lim
Vrije Universiteit Amsterdam(NL)
Publications by Year
Research Areas
Receptor Mechanisms and Signaling, Mast cells and histamine, Asthma and respiratory diseases, Neuropeptides and Animal Physiology, Chemokine receptors and signaling
Most-Cited Works
- → Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists(2020)353 cited
- → Evaluation of Histamine H1-, H2-, and H3-Receptor Ligands at the Human Histamine H4 Receptor: Identification of 4-Methylhistamine as the First Potent and Selective H4 Receptor Agonist(2005)276 cited
- → Fragment Based Design of New H4Receptor−Ligands with Anti-inflammatory Properties in Vivo(2008)179 cited
- → Molecular and biochemical pharmacology of the histamine H4receptor(2009)136 cited
- → Characterization of the Histamine H4Receptor Binding Site. Part 1. Synthesis and Pharmacological Evaluation of Dibenzodiazepine Derivatives(2006)133 cited
- → Discovery of S-(2-Guanidylethyl)-isothiourea (VUF 8430) as a Potent Nonimidazole Histamine H4 Receptor Agonist(2006)73 cited
- → Cloning and characterization of dominant negative splice variants of the human histamine H4 receptor(2008)65 cited
- → Delineation of Agonist Binding to the Human Histamine H4Receptor Using Mutational Analysis, Homology Modeling, and ab Initio Calculations(2008)58 cited
- → Molecular Determinants of Ligand Binding to H4R Species Variants(2010)55 cited
- → Several down, a few to go: histamine H3receptor ligands making the final push towards the market?(2011)54 cited