J. Willem M. Nissink
Babraham Institute(GB)AstraZeneca (Poland)(PL)
Publications by Year
Research Areas
Computational Drug Discovery Methods, Protein Structure and Dynamics, DNA Repair Mechanisms, Phagocytosis and Immune Regulation, Enzyme Structure and Function
Most-Cited Works
- → Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017—Utility and Limitations(2017)634 cited
- → Highly Stable Si−C Linked Functionalized Monolayers on the Silicon (100) Surface(1998)498 cited
- → A new test set for validating predictions of protein–ligand interaction(2002)429 cited
- → Modeling Water Molecules in Protein−Ligand Docking Using GOLD(2005)388 cited
- → Comparing protein–ligand docking programs is difficult(2005)361 cited
- → PAINS in the Assay: Chemical Mechanisms of Assay Interference and Promiscuous Enzymatic Inhibition Observed during a Sulfhydryl-Scavenging HTS(2015)346 cited
- → Discovery and Characterization of AZD6738, a Potent Inhibitor of Ataxia Telangiectasia Mutated and Rad3 Related (ATR) Kinase with Application as an Anticancer Agent(2018)321 cited
- → Discovery of 4-{4-[(3R)-3-Methylmorpholin-4-yl]-6-[1-(methylsulfonyl)cyclopropyl]pyrimidin-2-yl}-1H-indole (AZ20): A Potent and Selective Inhibitor of ATR Protein Kinase with Monotherapy in Vivo Antitumor Activity(2013)214 cited
- → Potent and Selective Inhibitors of MTH1 Probe Its Role in Cancer Cell Survival(2016)135 cited
- → Simple Size-Independent Measure of Ligand Efficiency(2009)112 cited