James X. Chen
The University of Texas MD Anderson Cancer Center(US)
Publications by Year
Research Areas
Carcinogens and Genotoxicity Assessment, Cancer-related Molecular Pathways, DNA Repair Mechanisms, Epigenetics and DNA Methylation, RNA modifications and cancer
Most-Cited Works
- → Cytosine methylation determines hot spots of DNA damage in the human P 53 gene(1997)334 cited
- Carcinogens preferentially bind at methylated CpG in the p53 mutational hot spots.(1998)
- Both (+/-)syn- and (+/-)anti-7,12-dimethylbenz[a]anthracene-3,4-diol-1,2-epoxides initiate tumors in mouse skin that possess -CAA- to -CTA- mutations at Codon 61 of c-H-ras.(2000)
- → Sequence Preference of 7,12-Dimethylbenz[a]anthracene-syn-diol Epoxide−DNA Binding in the Mouse H-ras Gene Detected by UvrABC Nucleases(1996)15 cited
- → Mapping polycyclic aromatic hydrocarbon and aromatic amine-induced DNA damage in cancer-related genes at the sequence level(2002)10 cited
- → Using UvrABC Nuclease To Detect 7,12-Dimethylbenz[a]anthracene anti-Diol Epoxide−DNA Binding Specificity in the Mouse H-ras Gene(1996)6 cited