Ngiap‐Kie Lim
Synthetic Biologics (United States)(US)
Publications by Year
Research Areas
Catalytic Cross-Coupling Reactions, Chemical Synthesis and Analysis, Synthetic Organic Chemistry Methods, Catalytic C–H Functionalization Methods, Asymmetric Hydrogenation and Catalysis
Most-Cited Works
- → Highly Stereoselective Synthesis of Tetrasubstituted Acyclic All-Carbon Olefins via Enol Tosylation and Suzuki–Miyaura Coupling(2017)98 cited
- → Design of a brain-penetrant CDK4/6 inhibitor for glioblastoma(2019)64 cited
- → Data Science-Enabled Palladium-Catalyzed Enantioselective Aryl-Carbonylation of Sulfonimidamides(2023)60 cited
- → Atroposelective Negishi Coupling Optimization Guided by Multivariate Linear Regression Analysis: Asymmetric Synthesis of KRAS G12C Covalent Inhibitor GDC-6036(2022)53 cited
- → Discovery of an Oxybenzylglycine Based Peroxisome Proliferator Activated Receptor α Selective Agonist 2-((3-((2-(4-Chlorophenyl)-5-methyloxazol-4-yl)methoxy)benzyl)(methoxycarbonyl)amino)acetic Acid (BMS-687453)(2010)40 cited
- → Enantioselective Sulfonimidamide Acylation via a Cinchona Alkaloid-Catalyzed Desymmetrization: Scope, Data Science, and Mechanistic Investigation(2024)40 cited
- → Synthesis of Selective Estrogen Receptor Degrader GDC-0810 via Stereocontrolled Assembly of a Tetrasubstituted All-Carbon Olefin(2018)29 cited
- → Macrolactamization Approaches to Arylomycin Antibiotics Core(2018)27 cited
- → Synthesis of Highly Stereodefined Tetrasubstituted Acyclic All-Carbon Olefins via a Syn-Elimination Approach(2017)27 cited
- → Process Development of Sotagliflozin, a Dual Inhibitor of Sodium–Glucose Cotransporter-1/2 for the Treatment of Diabetes(2020)22 cited