Iain Simpson
e-Therapeutics (United Kingdom)(GB)
Publications by Year
Research Areas
Synthesis and Catalytic Reactions, Immune cells in cancer, Mast cells and histamine, Cancer Research and Treatments, Chemical Synthesis and Analysis
Most-Cited Works
- → Identification and Characterization of Dual Inhibitors of the USP25/28 Deubiquitinating Enzyme Subfamily(2017)85 cited
- → Discovery of a Potent and Selective Oral Inhibitor of ERK1/2 (AZD0364) That Is Efficacious in Both Monotherapy and Combination Therapy in Models of Nonsmall Cell Lung Cancer (NSCLC)(2019)77 cited
- → Catalytic amidation of unactivated ester derivatives mediated by trifluoroethanol(2015)56 cited
- → Organobase-Catalyzed Amidation of Esters with Amino Alcohols(2013)54 cited
- → A modular lead-oriented synthesis of diverse piperazine, 1,4-diazepane and 1,5-diazocane scaffolds(2014)53 cited
- → Structure-Guided Discovery of Potent and Selective Inhibitors of ERK1/2 from a Modestly Active and Promiscuous Chemical Start Point(2017)52 cited
- → Discovery of novel imidazo[1,2-a]pyridines as inhibitors of the insulin-like growth factor-1 receptor tyrosine kinase(2011)48 cited
- → Modular, Gold-Catalyzed Approach to the Synthesis of Lead-like Piperazine Scaffolds(2013)44 cited
- → Matched molecular pair analysis of activity and properties of glycogen phosphorylase inhibitors(2008)42 cited
- → Novel imidazo[1,2-a]pyridine based inhibitors of the IGF-1 receptor tyrosine kinase: Optimization of the aniline(2011)40 cited